What are the Hunter criteria for serotonin syndrome?

Hunter criteria for serotonin syndrome 

Serotonin syndrome is associated with increased serotonergic activity, and the diagnosis is made on clinical grounds using the Hunter criteria. AKA the Hunter serotonin toxicity criteria.

To fulfil these criteria a patient must have taken a serotonergic agent and meet one 
of the following conditions: 
  • Spontaneous clonus 
  • Inducible clonus plus agitation or sweating 
  • Ocular clonus plus agitation or sweating 
  • Tremor plus hyperreflexia 
  • Hypertonia plus temperature>38°C plus ocular or inducible clonus
Available antidepressants

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