What is Cogan’s syndrome?

Cogan’s syndrome

It is a chronic inflammatory disorder characterized by interstitial keratitis together with vestibule-auditory symptoms. It may be associated with systemic vasculitis, particularly aortitis with the involvement of the aortic valve and may lead to the development of aortic aneurysms.
Glucocorticoids are the mainstay of treatment. Initiation of treatment as early as possible after the onset of hearing loss improves the likelihood of a favourable outcome.


Harrison’s Principles of Internal Medicine 2 volumes 19th Edition; page: 2192, 2204

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