What are the diagnostic criteria of Churg-Strauss Syndrome?

Diagnostic criteria of Churg-Strauss Syndrome

American college of Rheumatology 1990 criteria for Churg-Strauss syndrome 

The presence of 4 or more of the manifestations below is highly indicative of Churg-Strauss syndrome:
  • Asthma
  • Eosinophilia (10% on WCC differential)
  • Mononeuropathy or polyneuropathy
  • Migratory or transient pulmonary infiltrates
  • Systemic vasculitis (cardiac, renal, hepatic)
  • Extravascular eosinophils on a biopsy including artery, arteriole or venule.

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