What are the differences between down syndrome and cretinism?

Cretinism Vs Down syndrome

There is a close association between down syndrome and cretinism. Here is the difference between them.

Difference between down syndrome & cretinism:

Cretinism Down syndrome
Coarse facies Flat facies
Umbilical hernia present Umbilical hernia absent
Protruded abdomen Abdomen not protruded
Macroglossia present Normal tongue
H/O endemicity of Iodine Not so
TSH is high, T3& T4 is less These are normal
No karyotyping is needed Karyotyping is needed for dx

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